Case 1 Female late 40’s, thyroid lobectomy.
Worrisome histologic alterations following
fine-needle aspiration of the thyroid
pseudopapillary hyperplasia. There are a range of differential diagnoses
to this case including follicular adenoma or the clear cell change indicating a primary thyroid follicular
carcinoma or metastatic renal cell carcinoma
LiVolsi VA, Merino MJ. Worrisome
histologic alterations following fine-needle aspiration of the thyroid (WHAFFT). Pathol Annu
2 Female, late 30’s. High
right sided neck lump increasing in size nowhere near the thyroid, all tissue removed at surgery, ? lymph node
Ectopic thyroid tissue/parasitic sequestered
nodule is the diagnosis in this case although
the differential diagnosis is lateral aberrant thyroid. Although this
lesion appears follicular and there are
no features of papillary carcinoma there is always the remote
possibility that this could be a ‘lateral aberrant thyroid’ and that this latter diagnosis could not
be totally excluded.
3 Female, late 30’s, right
hemithyroidectomy. A G
ranular cell tumour of the thyroid, see also
higher power views
and here, reported in the literature in
isolated cases, and confirmed as S100+ve, TTF1-ve, AE1/AE3 –ve & MNF116 –ve (immunohistochemistry stains
are not shown).